As I stood in my kitchen, the rich aromas of melted butter and zesty parmesan enveloped me, instantly transporting me to the heart of Mississippi, where culinary traditions run deep. This Baked Catfish Allison is more than just a meal; it’s a love letter to the South, featuring perfectly baked catfish slathered in a creamy, savory sauce that will have everyone asking for seconds. Not only is it a quick and easy weeknight dinner solution, but it also brings a touch of comforting elegance to your table. You won’t need to be a seasoned chef to whip it up, making it a fantastic option for casual family gatherings or cozy date nights at home. So, what are you waiting for? Ready to dive into this Southern delight?

Why is Baked Catfish Allison a must-try?
Indulgent, this recipe combines the creaminess of mayonnaise and parmesan, creating a luscious sauce that beautifully complements the tender catfish. Southern charm shines through every bite, making it perfect for family gatherings or special occasions. Quick and easy, it takes minimal effort, allowing you to serve a delightful meal without spending hours in the kitchen. For a complete experience, serve it alongside sides like sautéed green beans or even some Baked Pesto Chicken for variety. Deliciously versatile, you can easily customize the flavors with different herbs or spices. Get ready to impress with this Southern staple!
Mississippi Oven Baked Catfish Ingredients
For the Baked Catfish
• Catfish fillets – Choose US farmed or thawed frozen fish for the best flavor.
• Salt – Enhances flavor; kosher salt is recommended for an even texture.
• Black pepper – Freshly ground black pepper elevates the seasoning profile.
For the Creamy Sauce
• Parmesan cheese – Offers depth; swap for pecorino for a sharper taste.
• Mayonnaise – Binds the ingredients for moisture; Greek yogurt is a lighter alternative.
• Butter (softened) – Adds richness; unsalted butter is preferred for better control.
• Green onions (sliced) – Provides freshness and crunch; consider using chives if preferred.
• Worcestershire Sauce – Adds umami notes; can be omitted in a pinch.
For the Heat
• Tabasco sauce – Adjust to taste for the spice level that suits you!
Step‑by‑Step Instructions for Mississippi Oven Baked Catfish Allison
Step 1: Preheat the Oven
Begin by preheating your oven to 350°F (175°C). While it warms up, take a moment to prepare your baking dish by lining it with non-stick foil or lightly greasing it with cooking spray. This ensures your catfish won’t stick and allows for easy cleanup after your delicious Mississippi Oven Baked Catfish Allison is ready to serve.
Step 2: Prepare the Sauce Mixture
In a medium-sized bowl, combine softened butter, grated parmesan cheese, Worcestershire sauce, mayonnaise, Tabasco sauce, and the sliced green onions. Season this mixture with salt and freshly ground black pepper to taste. Stir well until all ingredients are fully blended into a creamy sauce, creating a delicious topping for your catfish that will enhance its flavor beautifully.
Step 3: Season the Catfish
Gently pat the catfish fillets dry using paper towels to remove excess moisture. This step is crucial for achieving a nice golden crust. Once dry, season both sides of the fillets with salt and black pepper, ensuring even coverage. Now, place the seasoned fillets into your prepared baking dish, laying them side by side.
Step 4: Apply the Sauce
Using a spatula or the back of a spoon, spread the creamy sauce mixture evenly over the top of each catfish fillet. Ensure that the sauce generously covers the fillets to provide maximum flavor and keep them moist during baking. This step is vital for getting that rich, savory taste that defines the Mississippi Oven Baked Catfish Allison.
Step 5: Bake the Catfish
Slide the baking dish into your preheated oven and let the catfish bake for 20 to 25 minutes. The catfish is done when it flakes easily with a fork and the top is beautifully golden brown. If you desire a crispier texture, you can switch to the broiler for an additional few minutes, but watch closely to avoid burning.
Step 6: Serve and Savor
Once your Mississippi Oven Baked Catfish Allison is cooked to perfection, remove it from the oven and let it rest for a few minutes. This brief resting time allows the flavors to settle. Serve your catfish immediately, perhaps alongside sautéed green beans or creamy mashed potatoes, for a truly delightful meal that will impress family and friends.

What to Serve with Mississippi Oven Baked Catfish Allison
Escape into a world of flavors with sumptuous side dishes that elevate your baked catfish experience.
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Creamy Mashed Potatoes: A classic pairing, these buttery mashed potatoes soak up the rich juices from the catfish, creating a comforting combination. Their creamy texture beautifully contrasts the flaky fish, making each bite a delight.
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Sautéed Green Beans: Fresh and vibrant, sautéed green beans add a crisp texture and a pop of color to your plate. They provide a refreshing balance to the richness of the catfish.
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Hush Puppies: Deep-fried perfection, these fluffy cornmeal balls offer a delightful crunch and a hint of sweetness, embodying Southern charm that complements the baked catfish excellently.
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Coleslaw: A tangy, crunchy slaw brings a refreshing element to the meal. The acidity cuts through the richness of the fish, enhancing every flavorful bite.
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Cornbread: Moist and slightly sweet, cornbread is the ultimate Southern side. It pairs deliciously with the catfish sauce, providing that perfect bite of comfort food.
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Sweet Tea: This iconic Southern beverage embodies warmth and tradition, making your meal complete. The sweetness of the tea balances the savory, cheesy catfish while refreshing your palate.
Indulging in these sides not only rounds out your dinner options but also ensures every gathering is infused with culinary love.
Expert Tips for Mississippi Oven Baked Catfish Allison
- Quality Fish: Choose fresh or properly thawed catfish fillets to ensure the best flavor and texture. Thicker fillets require a bit more bake time.
- Cheese Swap: If you’re aiming for a sharper taste, consider substituting parmesan with pecorino cheese. Just remember this can alter the richness!
- Perfectly Seasoned: Don’t skimp on seasoning the catfish fillets with salt and pepper. This simple step enhances the overall flavor of the Mississippi Oven Baked Catfish Allison.
- Broiler Use: If broiling for additional crispness, keep a close watch to prevent burning. It can go from golden to charred in moments!
- Leftover Love: To maintain quality, store any leftovers in an airtight container. When reheating, aim for gentle warmth to keep the fish moist.
Make Ahead Options
These Mississippi Oven Baked Catfish Allison are perfect for meal prep enthusiasts! You can prepare the creamy sauce mixture and season the catfish fillets up to 24 hours in advance. Simply mix together softened butter, parmesan cheese, Worcestershire sauce, mayonnaise, Tabasco sauce, and green onions, then store it in an airtight container in the refrigerator. Season the catfish and place it in the baking dish, ready for the oven. When you’re ready to bake, spread the chilled sauce over the fish and cook as instructed; it will be just as delicious and fresh. This allows you to enjoy a hearty meal on busy weeknights with minimal effort!
How to Store and Freeze Mississippi Oven Baked Catfish Allison
Fridge: Store leftover catfish in an airtight container for up to 3 days. Make sure it’s completely cooled before sealing to maintain moisture.
Freezer: For longer storage, wrap the baked catfish tightly in foil and place it in a freezer-safe bag. It can be frozen for up to 2 months.
Reheating: When ready to enjoy, thaw overnight in the fridge, then reheat in the oven at 350°F (175°C) for about 10-15 minutes until warmed through, ensuring the moisture from the sauce is preserved.
Texture Reminder: To keep the texture delightful, avoid reheating in the microwave as it may cause the catfish to become rubbery.
Mississippi Oven Baked Catfish Variations
Feel free to get creative with these delightful twists on the classic Baked Catfish Allison recipe!
- Dairy-Free: Substitute Parmesan cheese with nutritional yeast or a dairy-free cheese alternative for a creamy flavor without the dairy.
- Gluten-Free: Make this dish gluten-free by ensuring all sauces and ingredients are certified gluten-free, especially Worcestershire sauce.
- Herb-Infused: Add fresh herbs like dill or parsley to the sauce for an aromatic lift. The vibrant flavors add an exciting boost to this classic dish!
- Lemon Zest: Incorporate lemon zest into the sauce for a zesty brightness. This twist can elevate the flavors and create a refreshing taste experience.
- Spice Level: For a spicy kick, mix in more Tabasco sauce or add a sprinkle of cayenne pepper to the seasoning. Adjust to your preference for heat!
- Veggie Boost: Layer some fresh vegetables like sliced tomatoes or bell peppers beneath the catfish in the baking dish. It’s a wonderful way to include more color and nutrition.
- Different Fish: Explore the ocean by swapping catfish for tilapia or cod. Each fish offers a unique flavor profile while maintaining the delicious essence of this dish.
- Creamy Spinach: Mix in some cooked spinach to the sauce for added nutrition and a beautiful pop of color. This variation not only looks lovely but is packed with goodness!
Transform your meal with these variations, and while you’re at it, consider serving it with some Delicious Pumpkin Pie Stuffed Baked Apples for dessert. Enjoy every creative bite!

Mississippi Oven Baked Catfish Allison Recipe FAQs
What type of catfish should I use for this recipe?
Absolutely! For the best flavor and texture, I recommend using fresh or properly thawed US farmed catfish fillets. If using frozen, make sure they are completely thawed before cooking to ensure even baking.
How long can I store leftovers?
Very importantly, you can store leftover Mississippi Oven Baked Catfish Allison in an airtight container in the refrigerator for up to 3 days. Just be sure to let it cool completely before sealing to keep all that moisture trapped in!
Can I freeze the baked catfish?
Yes, you can! To freeze this delightful dish, wrap the baked catfish tightly in aluminum foil and place it in a freezer-safe bag. It can last for up to 2 months in the freezer. Thaw it overnight in the refrigerator when you’re ready to enjoy it again.
How do I reheat the catfish without losing its texture?
Great question! To preserve the moistness and delicate texture, avoid using the microwave. Instead, thaw it overnight if frozen, then reheat in the oven at 350°F (175°C) for about 10-15 minutes. This way, you’ll keep the catfish flavorful and tender!
What if I have allergies to some of the ingredients?
If you have dietary restrictions, swapping ingredients can easily be done! For instance, you can substitute mayonnaise with Greek yogurt for a lighter option. If you’re allergic to fish, I suggest trying the sauce on a different protein, like chicken, for a similar flavor experience without the risk.
How do I know when the catfish is perfectly cooked?
Look for that lovely golden brown crust! The catfish is done when it flakes easily with a fork—this usually takes about 20-25 minutes of baking time. If you want a crispier topping, broil it for the last few minutes for that perfect golden finish.

Mississippi Oven Baked Catfish Allison: A Flavorful Feast
Ingredients
Equipment
Method
- Preheat your oven to 350°F (175°C) and prepare your baking dish.
- In a medium bowl, combine softened butter, grated parmesan, Worcestershire sauce, mayonnaise, Tabasco sauce, and sliced green onions. Season with salt and pepper, and stir until blended.
- Pat the catfish fillets dry and season both sides with salt and black pepper. Place them in your prepared baking dish.
- Spread the creamy sauce mixture evenly over the catfish fillets.
- Bake for 20 to 25 minutes, or until the catfish flakes easily and the top is golden brown. For extra crispness, broil for a few minutes.
- Let the catfish rest for a few minutes before serving, optionally with sides like sautéed green beans.

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